• Genetic Engineering Will Change Everything Forever – CRISPR

    Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly. Support us on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h Kurzgesagt merch here: http://bit.ly/1P1hQIH Get the music of the video here: soundcloud: http://bit.ly/2aRxNZd bandcamp: http://bit.ly/2berrSW http://www.epic-mountain.com Thanks to Volker Henn, James Gurney and (prefers anonymity) for help with this video! THANKS A LOT TO OUR LOVELY PATRONS FOR SUPPORTING US: Jeffrey Schneider, Konstantin Kaganovich, Tom Leiser, Archie Castillo, Russell Eishard, Ben Kershaw, Marius Stollen, H...

    published: 10 Aug 2016
  • 8 Monsters Created By Genetic Modification

    From Super-strong cows, to human-animal hybrids - here are 8 monsters you should avoid at all cost. And they're real too. https://eskify.com Facebook https://www.facebook.com/EskifyMedia/ MORE LISTS https://www.youtube.com/channel/UCtNdZrjjurSTFv-JgvQjssw Twitter https://twitter.com/EskifyMedia Google+ https://plus.google.com/u/0/ Image attributions: 3:59 – copyright https://www.flickr.com/people/24810268@N05 // (CC BY 2.0) https://creativecommons.org/licenses/by/2.0/deed.en Background music credit: Cool Vibes Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 License http://creativecommons.org/licenses/by/3.0/

    published: 11 May 2016
  • How To Change Our Own Genes

    It's called epigenetics and according to new research, it can influence everything from a human's weight to a small animal's propensity to fall in love. And as Anthony tells us, small life changes actually give us control to how these genes are expressed. Read More: Gene switches make prairie voles fall in love http://www.nature.com/news/gene-switc... "Epigenetic changes affect neurotransmitters that lead to pair-bond formation." Mom's gastric bypass surgery might benefit her offspring's DNA http://www.theverge.com/2013/6/1/4384... "When a woman undergoes weight loss surgery, her own body isn't the only one affected: children born to women after they've undergone gastric bypass procedures exhibit key genetic differences compared to siblings born prior to the surgeries." Differential met...

    published: 05 Jun 2013
  • Chapter 14 Lesson Manipulating DNA

    Chapter 14 Lesson Manipulating DNA

    published: 10 Mar 2015
  • Molecular Biology

    Paul Andersen explains the major procedures in molecular biology. He starts with a brief description of Taq polymerase extracted from the hot pools of Yellowstone Park. He then uses the analogy of the ransom note to explain each of the processes that are required in genetic engineering. He explains how DNA is cut using restriction enzymes and glued using hydrogen bonds. He explains how gel electrophoresis can be used to sort DNA according to length and how the Polymerase Chain Reaction can be used to copy DNA. He finishes with a brief description of DNA sequencing. Intro Music Atribution Title: I4dsong_loop_main.wav Artist: CosmicD Link to sound: http://www.freesound.org/people/CosmicD/sounds/72556/ Creative Commons Atribution License

    published: 30 Apr 2012
  • DNA cloning

    DNA cloning animation - This lecture explains about the DNA cloning techniques with vectors. http://shomusbiology.com/ Source: Lodish, et al., Molecular Cell Biology, Fifth Edition, W. H. Freeman & Co. © 2004 W. H. Freeman & Co., and Sumanas, Inc. Link- http://www.sumanasinc.com/webcontent/animations/content/plasmidcloning.html For more information, log on to- http://shomusbiology.com/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of...

    published: 26 Dec 2012
  • Genetically modified human embryos: Chinese scientists raise concerns after editing embryo DNA

    Scientists worldwide have renewed calls for a halt to controversial human embryo research after a team of Chinese scientists published a paper on the genetic editing of human embryos. Researchers at Sun Yat-sen University in Guangzhou, China hoped to modify a gene in chromosome 11 responsible for beta-thalassemia, a genetic mutation that reduces the production of hemoglobin and results in lack of oxygen in the body. The embryos used in the research each had 69 chromosomes after being fertilized by two sperms. This extra set of chromosomes meant they could not result in a live birth. The research involved injecting the embryos with the enzyme complex CRISPR/Cas9, which splices DNA at specific locations. Researchers can then modify the problematic gene causing beta-thalassemia by program...

    published: 24 Apr 2015
  • F215 OCR A2 Biology - Genetic Engineering + Insulin

    I cover Genetic Engineering, all the enzymes used, how DNA is extracted, and how cells are modified to produce insulin protein.

    published: 20 May 2015
  • Splicing and Dicing DNA: Genome Engineering and the CRISPR Revolution

    CRISPR: It’s the powerful gene editing technology transforming biomedical research. Fast, cheap and easy to use, it allows scientists to rewrite the DNA in just about any organism—including humans—with tests on human embryos already underway. The technique’s potential to radically reshape everything from disease prevention to the future of human evolution has driven explosive progress and heated debate. Join the world’s CRISPR pioneers to learn about the enormous possibilities and ethical challenges as we stand on the threshold of a brave new world of manipulating life’s fundamental code. Subscribe to our YouTube Channel for all the latest from WSF. Visit our Website: http://www.worldsciencefestival.com/ Like us on Facebook: https://www.facebook.com/worldsciencefestival Follow us on twitt...

    published: 09 Aug 2016
  • Transhumanism Spiritual Movement and Genetic Manipulation 2016 - 2017

    ^Be sure to Subscribe for more videos like this^ Transhumanism Exposed / Transhumanism documentary on transhumanism genetic manipulation. Website for LastDay'sAdvent http://www.lastdaysadvent.com/ end times signs end times news prophecy alert The transhumanist movement is a movement that is spiritual. Some claim out right that it is a new form of spirituality as Ray Kurzweil does in his book the age of spiritual machines. This kind of spirituality puts hope in something that does not guarantee peace, it just offers hope like a band aid. Have you ever heard of the saying who really wants to live forever? That comes from an inherent knowledge that this world will never really satisfy you. Do you agree or disagree? Will it ever be enough, or should we trust that there is a greater ...

    published: 07 Jan 2017
  • Richard Dawkins: The Dangers of CRISPR, Designer Babies, and Artificial Genetic Mutation

    Announcement of CRISPR technology, which allows precise editing of the human genome, has been heralded as the future of individualized medicine, and a decried as a slippery slope to engineering individual human qualities. Of course, humans already know how to manipulate animal genomes through selective breeding, but there has been no appetite to try on humans what is the norm for dogs. That's a good thing, says Dawkins. The results could well be dangerous. Does technology as a whole represent a threat to human welfare if it continues to evolve at its current rate? Not so fast, warns Dawkins. Comparing biological evolution to technological progress is an analogy at best. His newest book is Science in the Soul: Selected Writings of a Passionate Rationalist. Read more at BigThink.com: http:/...

    published: 21 Aug 2017
  • Genetically Modified Soldiers DARPA: The Mutant Wars

    http://experimentalvaccines.org/2012/09/21/genetically-modified-soldiers-darpa-the-mutant-wars/ I never thought I would be talking about genetically modified people outside of pitching some new science fiction movie to the predictive programming industry called Hollywood. Instead I find the government admitting to secret tests being conducted on soldiers in order to genetically modify their abilities. The agency in charge of this Island of doctor Moreau research just happens to be the same department responsible for making drones and surveillance robots that will be used to gather up dissedents during the coming conflagration. The Defense Advanced Research Projects Agency (DARPA) is an agency of the United States Department of Defense that receive over 2 billion dollars annually to conduc...

    published: 22 Sep 2012
  • 48. Gene Technology 1 of 6

    Genetic technology refers to the artificial manipulation of DNA and genes. This video looks at the tools and techniques involved in genetic technology. The tools include genetic scissors - called restriction enzymes, a genetic joining enzyme called ligase, as well as the use of DNA probes to show up and mark different sequences of DNA. We then look at genetic techniques - how to make lots of copies of DNA using the polymerase chain reaction; how to sort DNA fragments according to size in electrophoreses; then how to take this further and make it usable using the Southern Blot. Finally we look at some of the tricks that can be done using these tools and techniques - such as DNA profiling and fingerprinting; how to sequence DNA - from a molecule to a letter code we can interpret; and fin...

    published: 25 Jun 2010
  • Why Genetic Modification Is About To Get Easier

    How do we modify our genes, and is it ethical? Read More: Altering genes with the aid of light http://www.sciencedaily.com/releases/2015/05/150508140342.htmScientists have been manipulating genes for a while. Now researchers have found a way to control the process with higher precision, by using light.” America Needs To Figure Out The Ethics Of Gene Editing Now http://www.wired.com/2015/04/america-needs-figure-ethics-gene-editing-now/ ____________________ DNews is dedicated to satisfying your curiosity and to bringing you mind-bending stories & perspectives you won't find anywhere else! New videos twice daily. Watch More DNews on TestTube http://testtube.com/dnews Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel DNews on Twitter http...

    published: 01 Jul 2015
  • Cre-LoxP Recombination

    This video discusses the mechanisms behind the Cre-LoxP Recombination, which has been used in many research studies to manipulate genes. Specifically, we use the example of excising a lacZ stop site to label cells in order to perform Pulse Chase Experiments.

    published: 25 Nov 2015
  • The clock in our genes and in every cell of your body | Joseph Takahashi | TEDxSMU 2013

    Joseph S. Takahashi, Ph.D. is the Loyd B. Sands Distinguished Chair in Neuroscience, an Investigator of the Howard Hughes Medical Institute, and Chair of the Department of Neuroscience at the University of Texas Southwestern Medical Center in Dallas. His research interests are the molecular mechanism of circadian clocks, neuroscience, and the genetic basis of behavior. Dr. Takahashi pioneered the use of genetics in the mouse as a tool for discovery of genes underlying neurobiology and behavior. His awards include the Honma International Prize in Biological Rhythms Research in 1986, W. Alden Spencer Award in Neuroscience from Columbia University in 2001, Eduard Buchner Prize from German Society for Biochemistry and Molecular Biology in 2003 and Outstanding Scientific Achievement Award from ...

    published: 21 Nov 2013
  • The Moth: Self-Manipulating Depression - Lone Frank

    Journalist and Author Lone Frank faces her destiny when she learns she won't be able to escape mental illness. The World Science Festival and The Moth team up to bring to the stage scientists, writers and artists to tell stories of their personal relationships with science. The tales you'll hear in these videos are personal triumphs, challenges and discoveries...all relating to the power of science. Watch them all in http://worldsciencefestival.com/series/The_Moth. Original Program date: May 31, 2013 The World Science Festival gathers great minds in science and the arts to produce live and digital content that allows a broad general audience to engage with scientific discoveries. Our mission is to cultivate a general public informed by science, inspired by its wonder, convinced of its ...

    published: 11 Apr 2014
  • Manolis Kellis - From genomics to precision medicine - Uncovering and manipulating the genetic circu

    Watch on LabRoots at http://labroots.com/webcast/id/696 Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent revolution in human genetic studies, which resulted in thousands of disease-associated regions. However, translating genetic results into mechanistic insights remains an unsolved challenge, partly because in 90% of cases, disease-associated common variants do not affect protein function directly, but instead alter genomic control elements that govern gene expression patterns. To systematically characterize these control elements and their circuitry, we generated epigenomic maps of 127 primary human tissues and cell types, and networks linking the...

    published: 25 Feb 2016
  • DNA - Episode 2 of 5 - Playing.God - PBS Documentary

    In 1973 two scientists undertook an experiment which rocked the world. By transferring DNA from one species to another, Herb Boyer and Stan Cohen became the first Genetic Engineers. Their experimrnt triggerd a wave of controversy about the dangers of genetic manupulation, but it also generated a multi billion dollar industry. Biotechnology would soon transform the pharmaceutical industry and genetically modified food was to herald the biggest revolution in agriculture since the industrialization of farming. Yet the public was skeptical, and so were certain scientists. Some feared that a cancer-causing gene stitched into the DNA of a bacterium might be accidentally absorbed in the human gut, enabling cancer to be passed on like an infectious disease. Biologists from all over the world were...

    published: 21 Mar 2013
  • THW legalize current technologies for manipulating the genetic characteristics of human embryos

    published: 02 May 2017
  • Genome Editing with CRISPR-Cas9

    This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at http://zlab.mit.edu . Images and footage courtesy of Sputnik Animation, the Broad Institute of MIT and Harvard, Justin Knight and pond5.

    published: 05 Nov 2014
  • DNA cloning and recombinant DNA | Biomolecules | MCAT | Khan Academy

    Introduction to DNA cloning. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/dna-technology/v/hybridization-microarray?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/dna-technology/v/dna-libraries-generating-cdna?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to...

    published: 02 Jun 2016
  • Genetic engineering: The world's greatest scam?

    (French version -- http://www.greenpeace.org/ogm) Genetic engineering is a threat to food security, especially in a changing climate. The introduction of genetically manipulated organisms by choice or by accident grossly undermines sustainable agriculture and in so doing, severely limits the choice of food we can eat. Once GE plants are released into the environment, they are out of control. If anything goes wrong - they are impossible to recall. GE contamination threatens biodiversity respected as the global heritage of humankind, and one of our world's fundamental keys to survival.

    published: 11 Sep 2009
  • DNA Structure and Replication: Crash Course Biology #10

    Hank introduces us to that wondrous molecule deoxyribonucleic acid - also known as DNA - and explains how it replicates itself in our cells. Crash Course Biology is now available on DVD! http://dftba.com/product/1av/CrashCourse-Biology-The-Complete-Series-DVD-Set Like CrashCourse on Facebook: http://www.facebook.com/YouTubeCrashCourse Follow CrashCourse on Twitter: http://www.twitter.com/TheCrashCourse References for this episode can be found in the Google document here: http://dft.ba/-2hCl 1:41 link to Biological Molecules http://www.youtube.com/watch?v=H8WJ2KENlK0 Table of Contents: 1) Nucleic Acids 1:30 2) DNA -A) Polymers 1:53 -B) Three Ingredients 2:12 -C) Base Pairs 3:45 -D) Base Sequences 4:13 3) Pop Quiz 5:07 4) RNA 5:36 -A) Three Differences from DNA 5:43 5) Biolography 6:16 ...

    published: 02 Apr 2012
Genetic Engineering Will Change Everything Forever – CRISPR

Genetic Engineering Will Change Everything Forever – CRISPR

  • Order:
  • Duration: 16:04
  • Updated: 10 Aug 2016
  • views: 6592251
videos
Designer babies, the end of diseases, genetically modified humans that never age. Outrageous things that used to be science fiction are suddenly becoming reality. The only thing we know for sure is that things will change irreversibly. Support us on Patreon so we can make more videos (and get cool stuff in return): https://www.patreon.com/Kurzgesagt?ty=h Kurzgesagt merch here: http://bit.ly/1P1hQIH Get the music of the video here: soundcloud: http://bit.ly/2aRxNZd bandcamp: http://bit.ly/2berrSW http://www.epic-mountain.com Thanks to Volker Henn, James Gurney and (prefers anonymity) for help with this video! THANKS A LOT TO OUR LOVELY PATRONS FOR SUPPORTING US: Jeffrey Schneider, Konstantin Kaganovich, Tom Leiser, Archie Castillo, Russell Eishard, Ben Kershaw, Marius Stollen, Henry Bowman, Ben Johns, Bogdan Radu, Sam Toland, Pierre Thalamy, Christopher Morgan, Rocks Arent People, Ross Devereux, Pascal Michaud, Derek DuBreuil, Sofia Quintero, Robert Swiniarski, Merkt Kızılırmak, Michelle Rowley, Andy Dong, Saphir Patel, Harris Rotto, Thomas Huzij, Ryan James Burke, NTRX, Chaz Lewis, Amir Resali, The War on Stupid, John Pestana, Lucien Delbert, iaDRM, Jacob Edwards, Lauritz Klaus, Jason Hunt, Marcus : ), Taylor Lau, Rhett H Eisenberg, Mr.Z, Jeremy Dumet, Fatman13, Kasturi Raghavan, Kousora, Rich Sekmistrz, Mozart Peter, Gaby Germanos, Andreas Hertle, Alena Vlachova, Zdravko Šašek SOURCES AND FURTHER READING: The best book we read about the topic: GMO Sapiens https://goo.gl/NxFmk8 (affiliate link, we get a cut if buy the book!) – Good Overview by Wired: http://bit.ly/1DuM4zq –timeline of computer development: http://bit.ly/1VtiJ0N – Selective breeding: http://bit.ly/29GaPVS – DNA: http://bit.ly/1rQs8Yk – Radiation research: http://bit.ly/2ad6wT1 – inserting DNA snippets into organisms: http://bit.ly/2apyqbj – First genetically modified animal: http://bit.ly/2abkfYO – First GM patent: http://bit.ly/2a5cCox – chemicals produced by GMOs: http://bit.ly/29UvTbh http://bit.ly/2abeHwU http://bit.ly/2a86sBy – Flavr Savr Tomato: http://bit.ly/29YPVwN – First Human Engineering: http://bit.ly/29ZTfsf – glowing fish: http://bit.ly/29UwuJU – CRISPR: http://go.nature.com/24Nhykm – HIV cut from cells and rats with CRISPR: http://go.nature.com/1RwR1xI http://ti.me/1TlADSi – first human CRISPR trials fighting cancer: http://go.nature.com/28PW40r first human CRISPR trial approved by Chinese for August 2016: http://go.nature.com/29RYNnK – genetic diseases: http://go.nature.com/2a8f7ny – pregnancies with Down Syndrome terminated: http://bit.ly/2acVyvg ( 1999 European study) – CRISPR and aging: http://bit.ly/2a3NYAV http://bit.ly/SuomTy http://go.nature.com/29WpDj1 http://ti.me/1R7Vus9 Help us caption & translate this video! http://www.youtube.com/timedtext_cs_panel?c=UCsXVk37bltHxD1rDPwtNM8Q&tab=2
https://wn.com/Genetic_Engineering_Will_Change_Everything_Forever_–_Crispr
8 Monsters Created By Genetic Modification

8 Monsters Created By Genetic Modification

  • Order:
  • Duration: 5:54
  • Updated: 11 May 2016
  • views: 407312
videos
From Super-strong cows, to human-animal hybrids - here are 8 monsters you should avoid at all cost. And they're real too. https://eskify.com Facebook https://www.facebook.com/EskifyMedia/ MORE LISTS https://www.youtube.com/channel/UCtNdZrjjurSTFv-JgvQjssw Twitter https://twitter.com/EskifyMedia Google+ https://plus.google.com/u/0/ Image attributions: 3:59 – copyright https://www.flickr.com/people/24810268@N05 // (CC BY 2.0) https://creativecommons.org/licenses/by/2.0/deed.en Background music credit: Cool Vibes Kevin MacLeod (incompetech.com) Licensed under Creative Commons: By Attribution 3.0 License http://creativecommons.org/licenses/by/3.0/
https://wn.com/8_Monsters_Created_By_Genetic_Modification
How To Change Our Own Genes

How To Change Our Own Genes

  • Order:
  • Duration: 3:03
  • Updated: 05 Jun 2013
  • views: 172417
videos
It's called epigenetics and according to new research, it can influence everything from a human's weight to a small animal's propensity to fall in love. And as Anthony tells us, small life changes actually give us control to how these genes are expressed. Read More: Gene switches make prairie voles fall in love http://www.nature.com/news/gene-switc... "Epigenetic changes affect neurotransmitters that lead to pair-bond formation." Mom's gastric bypass surgery might benefit her offspring's DNA http://www.theverge.com/2013/6/1/4384... "When a woman undergoes weight loss surgery, her own body isn't the only one affected: children born to women after they've undergone gastric bypass procedures exhibit key genetic differences compared to siblings born prior to the surgeries." Differential methylation in glucoregulatory genes of offspring born before vs. after maternal gastrointestinal bypass surgery http://www.pnas.org/content/early/201... "Obesity and overnutrition during pregnancy affect fetal programming of adult disease. Children born after maternal bariatric gastrointestinal bypass surgery (AMS) are less obese and exhibit improved cardiometabolic risk profiles carried into adulthood compared with siblings born before maternal surgery (BMS)." Stress makes you sick by changing your genes http://io9.com/5936173/stress-makes-y... "Most of us are well aware that stress dramatically heightens our susceptibility to contracting illnesses — both physical and psychological." Why Your DNA Isn't Your Destiny http://www.time.com/time/magazine/art... "At its most basic, epigenetics is the study of changes in gene activity that do not involve alterations to the genetic code but still get passed down to at least one successive generation." Nucleus accumbens dopamine differentially mediates the formation and maintenance of monogamous pair bonds http://www.nature.com/neuro/journal/v... "The involvement of dopamine within the nucleus accumbens in the formation and maintenance of pair bonds was assessed in a series of experiments using the monogamous prairie vole." Histone deacetylase inhibitors facilitate partner preference formation in female prairie voles http://www.nature.com/neuro/journal/v... "In the socially monogamous prairie vole (Microtus ochrogaster), mating induces enduring pair-bonds that are initiated by partner preference formation and regulated by a variety of neurotransmitters, including oxytocin, vasopressin and dopamine." The Role of Methylation in Gene Expression http://www.nature.com/scitable/topicp... "Not all genes are active at all times. DNA methylation is one of several epigenetic mechanisms that cells use to control gene expression." Is Our Health Determined By Our Genes? http://www.huffingtonpost.com/dr-fran... "Epigenetics is the study of molecular mechanisms by which our environment controls our gene activity." Watch More: Sleep Loss Screws Your Genes http://www.youtube.com/watch?&v=fAuzUt4170A So Much Junk DNA http://www.youtube.com/watch?&v=uX7Okcqe8eU Love Stinks http://www.youtube.com/watch?&v=GYM0KXs8-To ____________________ DNews is dedicated to satisfying your curiosity and to bringing you mind-bending stories & perspectives you won't find anywhere else! New videos twice daily. Watch More DNews on TestTube http://testtube.com/dnews Subscribe now! http://www.youtube.com/subscription_c... DNews on Twitter http://twitter.com/dnews Anthony Carboni on Twitter http://twitter.com/acarboni Laci Green on Twitter http://twitter.com/gogreen18 Trace Dominguez on Twitter http://twitter.com/trace501 DNews on Facebook http://facebook.com/dnews DNews on Google+ http://gplus.to/dnews Discovery News http://discoverynews.com
https://wn.com/How_To_Change_Our_Own_Genes
Chapter 14 Lesson Manipulating DNA

Chapter 14 Lesson Manipulating DNA

  • Order:
  • Duration: 5:41
  • Updated: 10 Mar 2015
  • views: 1239
videos
Chapter 14 Lesson Manipulating DNA
https://wn.com/Chapter_14_Lesson_Manipulating_Dna
Molecular Biology

Molecular Biology

  • Order:
  • Duration: 14:33
  • Updated: 30 Apr 2012
  • views: 304998
videos
Paul Andersen explains the major procedures in molecular biology. He starts with a brief description of Taq polymerase extracted from the hot pools of Yellowstone Park. He then uses the analogy of the ransom note to explain each of the processes that are required in genetic engineering. He explains how DNA is cut using restriction enzymes and glued using hydrogen bonds. He explains how gel electrophoresis can be used to sort DNA according to length and how the Polymerase Chain Reaction can be used to copy DNA. He finishes with a brief description of DNA sequencing. Intro Music Atribution Title: I4dsong_loop_main.wav Artist: CosmicD Link to sound: http://www.freesound.org/people/CosmicD/sounds/72556/ Creative Commons Atribution License
https://wn.com/Molecular_Biology
DNA cloning

DNA cloning

  • Order:
  • Duration: 4:27
  • Updated: 26 Dec 2012
  • views: 228928
videos
DNA cloning animation - This lecture explains about the DNA cloning techniques with vectors. http://shomusbiology.com/ Source: Lodish, et al., Molecular Cell Biology, Fifth Edition, W. H. Freeman & Co. © 2004 W. H. Freeman & Co., and Sumanas, Inc. Link- http://www.sumanasinc.com/webcontent/animations/content/plasmidcloning.html For more information, log on to- http://shomusbiology.com/ Download the study materials here- http://shomusbiology.com/bio-materials.html Remember Shomu’s Biology is created to spread the knowledge of life science and biology by sharing all this free biology lectures video and animation presented by Suman Bhattacharjee in YouTube. All these tutorials are brought to you for free. Please subscribe to our channel so that we can grow together. You can check for any of the following services from Shomu’s Biology- Buy Shomu’s Biology lecture DVD set- www.shomusbiology.com/dvd-store Shomu’s Biology assignment services – www.shomusbiology.com/assignment -help Join Online coaching for CSIR NET exam – www.shomusbiology.com/net-coaching We are social. Find us on different sites here- Our Website – www.shomusbiology.com Facebook page- https://www.facebook.com/ShomusBiology/ Twitter - https://twitter.com/shomusbiology SlideShare- www.slideshare.net/shomusbiology Google plus- https://plus.google.com/113648584982732129198 LinkedIn - https://www.linkedin.com/in/suman-bhattacharjee-2a051661 Youtube- https://www.youtube.com/user/TheFunsuman Thank you for watching Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms.The use of the word cloning refers to the fact that the method involves the replication of a single DNA molecule starting from a single living cell to generate a large population of cells containing identical DNA molecules. Molecular cloning generally uses DNA sequences from two different organisms: the species that is the source of the DNA to be cloned, and the species that will serve as the living host for replication of the recombinant DNA. Molecular cloning methods are central to many contemporary areas of modern biology and medicine.[2] In a conventional molecular cloning experiment, the DNA to be cloned is obtained from an organism of interest, then treated with enzymes in the test tube to generate smaller DNA fragments. Subsequently, these fragments are then combined with vector DNA to generate recombinant DNA molecules. The recombinant DNA is then introduced into a host organism (typically an easy-to-grow, benign, laboratory strain of E. coli bacteria). This will generate a population of organisms in which recombinant DNA molecules are replicated along with the host DNA. Because they contain foreign DNA fragments, these are transgenic or genetically-modified microorganisms (GMO).[3] This process takes advantage of the fact that a single bacterial cell can be induced to take up and replicate a single recombinant DNA molecule. This single cell can then be expanded exponentially to generate a large amount of bacteria, each of which contain copies of the original recombinant molecule. Thus, both the resulting bacterial population, and the recombinant DNA molecule, are commonly referred to as "clones". Strictly speaking, recombinant DNA refers to DNA molecules, while molecular cloning refers to the experimental methods used to assemble them. Source of the article published in description is Wikipedia. I am sharing their material. © by original content developers of Wikipedia. Link- http://en.wikipedia.org/wiki/Main_Page
https://wn.com/Dna_Cloning
Genetically modified human embryos: Chinese scientists raise concerns after editing embryo DNA

Genetically modified human embryos: Chinese scientists raise concerns after editing embryo DNA

  • Order:
  • Duration: 2:09
  • Updated: 24 Apr 2015
  • views: 22984
videos
Scientists worldwide have renewed calls for a halt to controversial human embryo research after a team of Chinese scientists published a paper on the genetic editing of human embryos. Researchers at Sun Yat-sen University in Guangzhou, China hoped to modify a gene in chromosome 11 responsible for beta-thalassemia, a genetic mutation that reduces the production of hemoglobin and results in lack of oxygen in the body. The embryos used in the research each had 69 chromosomes after being fertilized by two sperms. This extra set of chromosomes meant they could not result in a live birth. The research involved injecting the embryos with the enzyme complex CRISPR/Cas9, which splices DNA at specific locations. Researchers can then modify the problematic gene causing beta-thalassemia by programming the enzyme complex to target that specific gene. Of the 86 embryos injected with the enzyme, only 71 survived the initial 48-hour period needed for CRISPR to replace the DNA. And of the 54 embryos that were tested, researchers found that only 28 had ‘successfully spliced,’ with a fraction of those 28 containing the replacement genetic material. The research team found a surprising number of mutations cropped up as a result of the CRISPR/Cas9 complex acting on parts of the genome other than the target area. Critics say the procedure could produce unknown effects on future generations as all modifications would be inheritable. ----------------------------------------­--------------------- Welcome to TomoNews, where we animate the most entertaining news on the internets. Come here for an animated look at viral headlines, US news, celebrity gossip, salacious scandals, dumb criminals and much more! Subscribe now for daily news animations that will knock your socks off. Visit our official website for all the latest, uncensored videos: http://us.tomonews.net Check out our Android app: http://bit.ly/1rddhCj Check out our iOS app: http://bit.ly/1gO3z1f Stay connected with us here: Facebook http://www.facebook.com/TomoNewsUS Twitter @tomonewsus http://www.twitter.com/TomoNewsUS Google+ http://plus.google.com/+TomoNewsUS/ Instagram @tomonewsus http://instagram.com/tomonewsus
https://wn.com/Genetically_Modified_Human_Embryos_Chinese_Scientists_Raise_Concerns_After_Editing_Embryo_Dna
F215 OCR A2 Biology - Genetic Engineering + Insulin

F215 OCR A2 Biology - Genetic Engineering + Insulin

  • Order:
  • Duration: 11:57
  • Updated: 20 May 2015
  • views: 10614
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I cover Genetic Engineering, all the enzymes used, how DNA is extracted, and how cells are modified to produce insulin protein.
https://wn.com/F215_Ocr_A2_Biology_Genetic_Engineering_Insulin
Splicing and Dicing DNA: Genome Engineering and the CRISPR Revolution

Splicing and Dicing DNA: Genome Engineering and the CRISPR Revolution

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  • Duration: 1:24:26
  • Updated: 09 Aug 2016
  • views: 154130
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CRISPR: It’s the powerful gene editing technology transforming biomedical research. Fast, cheap and easy to use, it allows scientists to rewrite the DNA in just about any organism—including humans—with tests on human embryos already underway. The technique’s potential to radically reshape everything from disease prevention to the future of human evolution has driven explosive progress and heated debate. Join the world’s CRISPR pioneers to learn about the enormous possibilities and ethical challenges as we stand on the threshold of a brave new world of manipulating life’s fundamental code. Subscribe to our YouTube Channel for all the latest from WSF. Visit our Website: http://www.worldsciencefestival.com/ Like us on Facebook: https://www.facebook.com/worldsciencefestival Follow us on twitter: https://twitter.com/WorldSciFest Original Program Date: June 3 2016 MODERATOR: Richard Besser PARTICIPANTS: George Church, Luke Dow, Josephine Johnston, Ben Matthews, Harry Ostrer, Noel Sauer What is CRISPR? 00:05 Introduction by Richard Besser 3:58 Participant Introductions. 5:02 What is so powerful about CRISPR? 7:25 How is CRISPR is used? 13:00 How will CRISPR help eliminate Zika Virus? 20:45 Modifying 60 genes at once in a pig. 26:02 What are potential agricultural advantages from CRISPR? 28:44 If you have eaten CRISPR cells? 35:00 Using a gene drives to eliminate virus? 37:40 Creating an off switch for CRISPR 40:27 How is it ethical to not rid the world of malaria? 42:55 What is the difference between editing a germ line and editing a cancer cell? 48:27 Why would the first CRISPR baby create backlash? 58:48 How do we regular CRISPR used in military applications? 1:06:33 What is the regulation to be expected from CRISPR? 1:13:09 What does a CRISPR-ised world look like? 1:16:00
https://wn.com/Splicing_And_Dicing_Dna_Genome_Engineering_And_The_Crispr_Revolution
Transhumanism Spiritual Movement and Genetic Manipulation 2016 - 2017

Transhumanism Spiritual Movement and Genetic Manipulation 2016 - 2017

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  • Duration: 22:26
  • Updated: 07 Jan 2017
  • views: 43300
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^Be sure to Subscribe for more videos like this^ Transhumanism Exposed / Transhumanism documentary on transhumanism genetic manipulation. Website for LastDay'sAdvent http://www.lastdaysadvent.com/ end times signs end times news prophecy alert The transhumanist movement is a movement that is spiritual. Some claim out right that it is a new form of spirituality as Ray Kurzweil does in his book the age of spiritual machines. This kind of spirituality puts hope in something that does not guarantee peace, it just offers hope like a band aid. Have you ever heard of the saying who really wants to live forever? That comes from an inherent knowledge that this world will never really satisfy you. Do you agree or disagree? Will it ever be enough, or should we trust that there is a greater purpose. That purpose is Christ, agree or disagree. Transhumanism (abbreviated as H+ or h+) is an international and intellectual movement that aims to transform the human condition by developing and making widely available sophisticated technologies to greatly enhance human intellectual, physical, and psychological capacities.[1][2] Transhumanist thinkers study the potential benefits and dangers of emerging technologies that could overcome fundamental human limitations, as well as the ethics[3] of using such technologies.[4] The most common transhumanist thesis is that human beings may eventually be able to transform themselves into different beings with abilities so greatly expanded from the natural condition as to merit the label of posthuman beings.[2] Artificial intelligence (AI) is intelligence exhibited by machines. In computer science, an ideal "intelligent" machine is a flexible rational agent that perceives its environment and takes actions that maximize its chance of success at some goal.[1] Colloquially, the term "artificial intelligence" is applied when a machine mimics "cognitive" functions that humans associate with other human minds, such as "learning" and "problem solving".[2] As machines become increasingly capable, mental facilities once thought to require intelligence are removed from the definition. For example, optical character recognition is no longer perceived as an exemplar of "artificial intelligence", having become a routine technology.[3] Capabilities currently classified as AI include successfully understanding human speech,[4] competing at a high level in strategic game systems (such as Chess and Go[5]), self-driving cars, and interpreting complex data. Some people also consider AI a danger to humanity if it progresses unabatedly.[6] AI research is divided into subfields[7] that focus on specific problems or on specific approaches or on the use of a particular tool or towards satisfying particular applications. According to some definitions of the term, the physical attachments humanity has with even the most basic technologies have already made them cyborgs.[4] In a typical example, a human with an artificial cardiac pacemaker or implantable cardioverter-defibrillator would be considered a cyborg, since these devices measure voltage potentials in the body, perform signal processing, and can deliver electrical stimuli, using this synthetic feedback mechanism to keep that person alive. Implants, especially cochlear implants, that combine mechanical modification with any kind of feedback response are also cyborg enhancements. Some theorists[who?] cite such modifications as contact lenses, hearing aids, or intraocular lenses as examples of fitting humans with technology to enhance their biological capabilities. As cyborgs currently are on the rise some theorists argue there is a need to develop new definitions of aging and for instance a bio-techno-social definition of aging has been suggested.[5] The term is also used to address human-technology mixtures in the abstract. This includes not only commonly used pieces of technology such as phones, computers, the Internet, etc. but also artifacts that may not popularly be considered technology; for example, pen and paper, and speech and language. Definitions from wikipedia https://en.wikipedia.org/wiki/Cyborg https://en.wikipedia.org/wiki/Transhumanism https://en.wikipedia.org/wiki/Artificial_intelligence key words transhumanism transhumanism 2016 transhumanism documentary transhumanism and genetic manipulation transhumanism illuminati transhumanism satan's genetic manipulation transhumanism 2017 transhumanism exposed transhumanism technology transhumanism gmm transhumanist agenda transhumanism and the bible transhumanism and immortality transhumanism ai genetic nano transhumanism and christianity
https://wn.com/Transhumanism_Spiritual_Movement_And_Genetic_Manipulation_2016_2017
Richard Dawkins: The Dangers of CRISPR, Designer Babies, and Artificial Genetic Mutation

Richard Dawkins: The Dangers of CRISPR, Designer Babies, and Artificial Genetic Mutation

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  • Duration: 4:08
  • Updated: 21 Aug 2017
  • views: 14029
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Announcement of CRISPR technology, which allows precise editing of the human genome, has been heralded as the future of individualized medicine, and a decried as a slippery slope to engineering individual human qualities. Of course, humans already know how to manipulate animal genomes through selective breeding, but there has been no appetite to try on humans what is the norm for dogs. That's a good thing, says Dawkins. The results could well be dangerous. Does technology as a whole represent a threat to human welfare if it continues to evolve at its current rate? Not so fast, warns Dawkins. Comparing biological evolution to technological progress is an analogy at best. His newest book is Science in the Soul: Selected Writings of a Passionate Rationalist. Read more at BigThink.com: http://bigthink.com/videos/how-far-should-we-go-to-manipulate-the-genetic-code-of-human-life Follow Big Think here: YouTube: http://goo.gl/CPTsV5 Facebook: https://www.facebook.com/BigThinkdotcom Twitter: https://twitter.com/bigthink Transcript: I think it’s - I’m a believer in the precautionary principle as I’ve just said, and I think we have to worry about possible consequences of things that we do, and the ability to edit our own genomes is one thing we ought to worry about. I’m not sure it’s so much an ethical problem as a more practical problem. What would the consequences be? Would the consequences be bad? And they might be. I think it’s worth noticing that long before CRISPR long before it became capable of editing our genomes in anyway we have been editing the genomes of domestic animals and plants by artificial selection, not artificial mutation, which is what we’re now talking about, but artificial selection. When you think that a Pekingese is a wolf, a modified wolf, a genetically modified wolf—modified not by directly manipulating genes but by choosing for breeding individuals who have certain characteristics, for example, a small stubbed nose, et cetera, and making a wolf turn into a Pekingese. And we’ve been doing that very successfully with domestic animals like dogs, cows, domestic plants like maize for a long time, we’ve never done that to humans or hardly at all. Hitler tried it but it’s never really been properly done with humans I’m glad to say. So if we’ve never done that with humans with the easy way, which is artificial selection, it’s not obvious why we would suddenly start doing it the difficult way, which is by direct genetic manipulation. There doesn’t seem to be any great eagerness to do it over the last few centuries anyway. A lot of people have problems with what they call designer babies. You could imagine a future scenario in which people go to a doctor and say, "Doctor, we want our baby to be a musical genius. Please edit the genes so that we have the same genes as the Bach family had or something like that to make them into a musical genius." I mean that horrifies many people. It’s got totally obvious why that’s anymore horrifying than parents who are ambitious for the musical future of their child forcing the child to practice the piano three hours a day. There are differences, of course, forcing it to practice is maybe unpleasant for the child but it doesn’t go into the next generation, changing the genes does so there is a difference there. But at least people who shudder with horror at a designer baby who’s a musical genius, people who shudderat horror at that, why don’t you shudder with horror at forcing a child to have music lessons when it doesn’t want to or practice music when it doesn’t want to? I think although there is an analogy between technological evolution and biological evolution, it’s dangerous to push that analogy too far. I’ve just been decrying the view that everybody is an expert. And I’m not an expert in technology and I think that every scientist needs to admit when they don’t know. The analogy is there, things change gradually, the evolution of the airplane starting from the Wright brothers in the beginning of the 20th century until the present, it’s been spectacularly fast but it is gradual evolution and it looks, to some extent, like biological evolution. But whether it occurs by natural selection that’s open to argument. You could say that it does occur by a form of natural selection, but it’s not the same kind of natural selection. So I don’t regard myself as a biological evolutionist as qualified to talk about technological evolution. I’m interested in the analogy but I think it only is an analogy and it doesn’t go too far.
https://wn.com/Richard_Dawkins_The_Dangers_Of_Crispr,_Designer_Babies,_And_Artificial_Genetic_Mutation
Genetically Modified Soldiers DARPA: The Mutant Wars

Genetically Modified Soldiers DARPA: The Mutant Wars

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  • Duration: 2:45
  • Updated: 22 Sep 2012
  • views: 80872
videos
http://experimentalvaccines.org/2012/09/21/genetically-modified-soldiers-darpa-the-mutant-wars/ I never thought I would be talking about genetically modified people outside of pitching some new science fiction movie to the predictive programming industry called Hollywood. Instead I find the government admitting to secret tests being conducted on soldiers in order to genetically modify their abilities. The agency in charge of this Island of doctor Moreau research just happens to be the same department responsible for making drones and surveillance robots that will be used to gather up dissedents during the coming conflagration. The Defense Advanced Research Projects Agency (DARPA) is an agency of the United States Department of Defense that receive over 2 billion dollars annually to conduct secret experimentations on soldiers and to create an Orwellian programmed robotic police force that will be used domestically as well as abroad. The manipulation of the human genome is perhaps the most disturbing demonstration of human arrogance this century has yet begun to exploit. DARPA has recently released some of the details to the genes they are manipulating and their expected expression and possible application. Here is a list of the current experimentations that have been conducted in secrecy on soldiers in the United States military or at least some of the recent confession from the military industrial pharmaceutical complex: • Do you want a soldier that can run faster than an Olympic Athlete? • Do you want a soldier that won't need food or sleep for days? • Do you want a soldier that can regrow lost limbs? • Do you want a soldier that can out lift Olympic weightlifters? • Do you want a soldier that can communicate telepathically? Read the rest and get the research links above thanks! Main Website: http://experimentalvaccines.org/ Facebook: http://www.facebook.com/experimentalvaccines Twitter: https://twitter.com/EVaccines Google Plus: https://plus.google.com/u/0/116248571435806736579/posts/p/pub SUBSCRIBE TO MY YOUTUBE CHANNEL: http://www.youtube.com/user/ExperimentalVaccines PLEASE SHARE THIS VIDEO
https://wn.com/Genetically_Modified_Soldiers_Darpa_The_Mutant_Wars
48. Gene Technology 1 of 6

48. Gene Technology 1 of 6

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  • Duration: 9:51
  • Updated: 25 Jun 2010
  • views: 103826
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Genetic technology refers to the artificial manipulation of DNA and genes. This video looks at the tools and techniques involved in genetic technology. The tools include genetic scissors - called restriction enzymes, a genetic joining enzyme called ligase, as well as the use of DNA probes to show up and mark different sequences of DNA. We then look at genetic techniques - how to make lots of copies of DNA using the polymerase chain reaction; how to sort DNA fragments according to size in electrophoreses; then how to take this further and make it usable using the Southern Blot. Finally we look at some of the tricks that can be done using these tools and techniques - such as DNA profiling and fingerprinting; how to sequence DNA - from a molecule to a letter code we can interpret; and finally we look at how cloning genes and the use of recombinant DNA technology allows us to mix the DNA of different species together. Lots of information. Always a joy.
https://wn.com/48._Gene_Technology_1_Of_6
Why Genetic Modification Is About To Get Easier

Why Genetic Modification Is About To Get Easier

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  • Duration: 3:40
  • Updated: 01 Jul 2015
  • views: 84363
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How do we modify our genes, and is it ethical? Read More: Altering genes with the aid of light http://www.sciencedaily.com/releases/2015/05/150508140342.htmScientists have been manipulating genes for a while. Now researchers have found a way to control the process with higher precision, by using light.” America Needs To Figure Out The Ethics Of Gene Editing Now http://www.wired.com/2015/04/america-needs-figure-ethics-gene-editing-now/ ____________________ DNews is dedicated to satisfying your curiosity and to bringing you mind-bending stories & perspectives you won't find anywhere else! New videos twice daily. Watch More DNews on TestTube http://testtube.com/dnews Subscribe now! http://www.youtube.com/subscription_center?add_user=dnewschannel DNews on Twitter http://twitter.com/dnews Trace Dominguez on Twitter https://twitter.com/tracedominguez Julia Wilde on Twitter https://twitter.com/julia_sci DNews on Facebook https://facebook.com/DiscoveryNews DNews on Google+ http://gplus.to/dnews Discovery News http://discoverynews.com Download the TestTube App: http://testu.be/1ndmmMq
https://wn.com/Why_Genetic_Modification_Is_About_To_Get_Easier
Cre-LoxP Recombination

Cre-LoxP Recombination

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  • Duration: 4:56
  • Updated: 25 Nov 2015
  • views: 60997
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This video discusses the mechanisms behind the Cre-LoxP Recombination, which has been used in many research studies to manipulate genes. Specifically, we use the example of excising a lacZ stop site to label cells in order to perform Pulse Chase Experiments.
https://wn.com/Cre_Loxp_Recombination
The clock in our genes and in every cell of your body | Joseph Takahashi | TEDxSMU 2013

The clock in our genes and in every cell of your body | Joseph Takahashi | TEDxSMU 2013

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  • Duration: 20:09
  • Updated: 21 Nov 2013
  • views: 19034
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Joseph S. Takahashi, Ph.D. is the Loyd B. Sands Distinguished Chair in Neuroscience, an Investigator of the Howard Hughes Medical Institute, and Chair of the Department of Neuroscience at the University of Texas Southwestern Medical Center in Dallas. His research interests are the molecular mechanism of circadian clocks, neuroscience, and the genetic basis of behavior. Dr. Takahashi pioneered the use of genetics in the mouse as a tool for discovery of genes underlying neurobiology and behavior. His awards include the Honma International Prize in Biological Rhythms Research in 1986, W. Alden Spencer Award in Neuroscience from Columbia University in 2001, Eduard Buchner Prize from German Society for Biochemistry and Molecular Biology in 2003 and Outstanding Scientific Achievement Award from the Sleep Research Society in 2012. He was elected a Fellow of the American Academy of Arts and Sciences in 2000, and a Member of the National Academy of Sciences in 2003. He was a co-founder of Hypnion, Inc., a biotech discovery company in Worcester, Mass., that investigated sleep/wake neurobiology and pharmaceuticals (now owned by Eli Lilly and Co.), and is a co-founder of ReSet Therapeutics, Inc., a biotech company that works on the role of clocks in metabolism. About TEDx: In the spirit of ideas worth spreading, TEDx is a program of local, self-organized events that bring people together to share a TED-like experience. At a TEDx event, TEDTalks video and live speakers combine to spark deep discussion and connection in a small group. These local, self-organized events are branded TEDx, where x = independently organized TED event. The TED Conference provides general guidance for the TEDx program, but individual TEDx events are self-organized.* (*Subject to certain rules and regulations)
https://wn.com/The_Clock_In_Our_Genes_And_In_Every_Cell_Of_Your_Body_|_Joseph_Takahashi_|_Tedxsmu_2013
The Moth: Self-Manipulating Depression - Lone Frank

The Moth: Self-Manipulating Depression - Lone Frank

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  • Duration: 16:00
  • Updated: 11 Apr 2014
  • views: 13396
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Journalist and Author Lone Frank faces her destiny when she learns she won't be able to escape mental illness. The World Science Festival and The Moth team up to bring to the stage scientists, writers and artists to tell stories of their personal relationships with science. The tales you'll hear in these videos are personal triumphs, challenges and discoveries...all relating to the power of science. Watch them all in http://worldsciencefestival.com/series/The_Moth. Original Program date: May 31, 2013 The World Science Festival gathers great minds in science and the arts to produce live and digital content that allows a broad general audience to engage with scientific discoveries. Our mission is to cultivate a general public informed by science, inspired by its wonder, convinced of its value, and prepared to engage with its implications for the future. Subscribe to our YouTube Channel for all the latest from WSF. Visit our Website: http://www.worldsciencefestival.com/ Like us on Facebook: https://www.facebook.com/worldscience... Follow us on twitter: https://twitter.com/WorldSciFest
https://wn.com/The_Moth_Self_Manipulating_Depression_Lone_Frank
Manolis Kellis - From genomics to precision medicine - Uncovering and manipulating the genetic circu

Manolis Kellis - From genomics to precision medicine - Uncovering and manipulating the genetic circu

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  • Duration: 53:20
  • Updated: 25 Feb 2016
  • views: 265
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Watch on LabRoots at http://labroots.com/webcast/id/696 Precision medicine requires understanding the mechanistic basis of complex disorders, and to precisely manipulate these mechanisms to better human health. This is partly enabled by the recent revolution in human genetic studies, which resulted in thousands of disease-associated regions. However, translating genetic results into mechanistic insights remains an unsolved challenge, partly because in 90% of cases, disease-associated common variants do not affect protein function directly, but instead alter genomic control elements that govern gene expression patterns. To systematically characterize these control elements and their circuitry, we generated epigenomic maps of 127 primary human tissues and cell types, and networks linking them to their target genes and their upstream regulators. We have used these maps and circuits to understand how human genetic variation contributes to disease and cancer, providing an unbiased view of disease genetics and sometimes re-shaping our understanding of common disorders. For example, we find evidence that genetic variants contributing to Alzheimer’s disease act primarily through immune processes, rather than neuronal processes. We also find that the strongest genetic association with obesity acts via a master switch controlling energy storage vs. energy dissipation in our adipocytes, rather than through the control of appetite in the brain. We have shown that we can manipulate these circuits by genome editing or gene targeting, opening up tissue-autonomous therapeutic avenues against the obesity epidemic. In addition to dissecting known disease-associated regions, we have combined genetic information with regulatory annotations and with epigenetic variation to discover new disease regions in cardiovascular disease, Alzheimer’s disease, and prostate cancer. These results span the spectrum of common, rare, and somatic variants, and illustrate the power and broad applicability of regulatory annotations and circuits for understanding human disease and cancer.
https://wn.com/Manolis_Kellis_From_Genomics_To_Precision_Medicine_Uncovering_And_Manipulating_The_Genetic_Circu
DNA - Episode 2 of 5 - Playing.God - PBS Documentary

DNA - Episode 2 of 5 - Playing.God - PBS Documentary

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  • Duration: 53:01
  • Updated: 21 Mar 2013
  • views: 236897
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In 1973 two scientists undertook an experiment which rocked the world. By transferring DNA from one species to another, Herb Boyer and Stan Cohen became the first Genetic Engineers. Their experimrnt triggerd a wave of controversy about the dangers of genetic manupulation, but it also generated a multi billion dollar industry. Biotechnology would soon transform the pharmaceutical industry and genetically modified food was to herald the biggest revolution in agriculture since the industrialization of farming. Yet the public was skeptical, and so were certain scientists. Some feared that a cancer-causing gene stitched into the DNA of a bacterium might be accidentally absorbed in the human gut, enabling cancer to be passed on like an infectious disease. Biologists from all over the world were called to a meeting in California to draw up a strict set of safety guidelines. When the panic subsided the stage was set for a biotechnology bonanza. A race began to produce genetically engineered insulin. A couple of years later a young researcher called Rob Horsch, who worked for the chemical giant Monsanto, produced the first genetically engineered plant. The biotech revolutions had arrived.
https://wn.com/Dna_Episode_2_Of_5_Playing.God_Pbs_Documentary
THW legalize current technologies for manipulating the genetic characteristics of human embryos

THW legalize current technologies for manipulating the genetic characteristics of human embryos

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  • Duration: 7:10
  • Updated: 02 May 2017
  • views: 79
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https://wn.com/Thw_Legalize_Current_Technologies_For_Manipulating_The_Genetic_Characteristics_Of_Human_Embryos
Genome Editing with CRISPR-Cas9

Genome Editing with CRISPR-Cas9

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  • Duration: 4:13
  • Updated: 05 Nov 2014
  • views: 1122796
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This animation depicts the CRISPR-Cas9 method for genome editing – a powerful new technology with many applications in biomedical research, including the potential to treat human genetic disease. Feng Zhang, a leader in the development of this technology, is a faculty member at MIT, an investigator at the McGovern Institute for Brain Research, and a core member of the Broad Institute. Further information can be found on Prof. Zhang’s website at http://zlab.mit.edu . Images and footage courtesy of Sputnik Animation, the Broad Institute of MIT and Harvard, Justin Knight and pond5.
https://wn.com/Genome_Editing_With_Crispr_Cas9
DNA cloning and recombinant DNA | Biomolecules | MCAT | Khan Academy

DNA cloning and recombinant DNA | Biomolecules | MCAT | Khan Academy

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  • Duration: 11:08
  • Updated: 02 Jun 2016
  • views: 111858
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Introduction to DNA cloning. Watch the next lesson: https://www.khanacademy.org/test-prep/mcat/biomolecules/dna-technology/v/hybridization-microarray?utm_source=YT&utm_medium=Desc&utm_campaign=mcat Missed the previous lesson? https://www.khanacademy.org/test-prep/mcat/biomolecules/dna-technology/v/dna-libraries-generating-cdna?utm_source=YT&utm_medium=Desc&utm_campaign=mcat MCAT on Khan Academy: Go ahead and practice some passage-based questions! About Khan Academy: Khan Academy offers practice exercises, instructional videos, and a personalized learning dashboard that empower learners to study at their own pace in and outside of the classroom. We tackle math, science, computer programming, history, art history, economics, and more. Our math missions guide learners from kindergarten to calculus using state-of-the-art, adaptive technology that identifies strengths and learning gaps. We've also partnered with institutions like NASA, The Museum of Modern Art, The California Academy of Sciences, and MIT to offer specialized content. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s MCAT channel: https://www.youtube.com/channel/UCDkK5wqSuwDlJ3_nl3rgdiQ?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
https://wn.com/Dna_Cloning_And_Recombinant_Dna_|_Biomolecules_|_Mcat_|_Khan_Academy
Genetic engineering: The world's greatest scam?

Genetic engineering: The world's greatest scam?

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  • Duration: 3:51
  • Updated: 11 Sep 2009
  • views: 527171
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(French version -- http://www.greenpeace.org/ogm) Genetic engineering is a threat to food security, especially in a changing climate. The introduction of genetically manipulated organisms by choice or by accident grossly undermines sustainable agriculture and in so doing, severely limits the choice of food we can eat. Once GE plants are released into the environment, they are out of control. If anything goes wrong - they are impossible to recall. GE contamination threatens biodiversity respected as the global heritage of humankind, and one of our world's fundamental keys to survival.
https://wn.com/Genetic_Engineering_The_World's_Greatest_Scam
DNA Structure and Replication: Crash Course Biology #10

DNA Structure and Replication: Crash Course Biology #10

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  • Duration: 12:59
  • Updated: 02 Apr 2012
  • views: 3931958
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Hank introduces us to that wondrous molecule deoxyribonucleic acid - also known as DNA - and explains how it replicates itself in our cells. Crash Course Biology is now available on DVD! http://dftba.com/product/1av/CrashCourse-Biology-The-Complete-Series-DVD-Set Like CrashCourse on Facebook: http://www.facebook.com/YouTubeCrashCourse Follow CrashCourse on Twitter: http://www.twitter.com/TheCrashCourse References for this episode can be found in the Google document here: http://dft.ba/-2hCl 1:41 link to Biological Molecules http://www.youtube.com/watch?v=H8WJ2KENlK0 Table of Contents: 1) Nucleic Acids 1:30 2) DNA -A) Polymers 1:53 -B) Three Ingredients 2:12 -C) Base Pairs 3:45 -D) Base Sequences 4:13 3) Pop Quiz 5:07 4) RNA 5:36 -A) Three Differences from DNA 5:43 5) Biolography 6:16 6) Replication 8:49 -A) Helicase and Unzipping 9:22 -B) Leading Strand 9:38 -C) DNA Polymerase 10:08 -D) RNA Primase 10:24 -E) Lagging Strand 10:46 -F) Okazaki Fragments 11:07 -F) DNA Ligase 11:47 DNA, deoxyribonucleic acid, chromosome, nucleic acid, ribonucleic acid, RNA, polymer, nucleotide, double helix, nucleotide base, base pair, base sequence, friedrich miescher, rosalind franklin, replication, helicase, leading strand, lagging strand, rna primase, dna polymerase, okazaki fragment Support CrashCourse on Subbable: http://subbable.com/crashcourse
https://wn.com/Dna_Structure_And_Replication_Crash_Course_Biology_10